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1

[Advances in Pharmacology] GABA Volume 54 || Structure, Pharmacology, and Function of GABAA Receptor Subtypes

Sieghart, Werner

Year:

2006

Language:

english

File:

PDF, 447 KB

english, 2006

2

Establishing a new mouse model for investigating the function of amygdala neurons in anxiety

Yvan Peterschmitt, Stefan Weger, Alexander Plauth, Regine Heilbronn, William Wisden, Günther Sperk, Werner Sieghart

Journal:

BMC Pharmacology

Year:

2008

Language:

english

File:

PDF, 75 KB

english, 2008

3

GABAA receptors: ligand-gated Cl− ion channels modulated by multiple drug-binding sites

Werner Sieghart

Journal:

Trends in Pharmacological Sciences

Year:

1992

Language:

english

File:

PDF, 809 KB

english, 1992

4

International Union of Basic and Clinical Pharmacology. CVI: GABA A Receptor Subtype- and Function-selective Ligands: Key Issues in Translation to Humans

Sieghart, Werner, Savić, Miroslav M., Ohlstein, Eliot H.

Journal:

Pharmacological Reviews

Year:

2018

Language:

english

File:

PDF, 2.85 MB

english, 2018

5

Immunohistochemical distribution of 10 GABA A receptor subunits in the forebrain of the rhesus monkey Macaca mulatta

Sperk, GÃ¼nther, Kirchmair, Elke, Bakker, Jaco, Sieghart, Werner, Drexel, Meinrad, Kondova, Ivanela

Journal:

The Journal of Comparative Neurology

Year:

2020

Language:

english

File:

PDF, 7.42 MB

english, 2020

6

Special relationship of ?-aminobutyric acid to the ventromedial nucleus of the hypothalamus during embryonic development

Tobet, Stuart A., Henderson, Rachel G., Whiting, Paul J., Sieghart, Werner

Journal:

The Journal of Comparative Neurology

Year:

1999

Language:

english

File:

PDF, 760 KB

english, 1999

7

Colocalization of multiple GABAA receptor subtypes with gephyrin at postsynaptic sites

Sasso�-Pognetto, Marco, Panzanelli, Patrizia, Sieghart, Werner, Fritschy, Jean-Marc

Journal:

The Journal of Comparative Neurology

Year:

2000

Language:

english

File:

PDF, 2.51 MB

english, 2000

8

Striatal efferents preferentially innervate neurons in the ventral pallidum containing GABAA receptor α 1 subunit-like immunoreactivity

Josef Marksteiner, Walter Kaufmann, Kristian Pfaller, Werner Sieghart, Alois Saria

Journal:

Year:

1996

Language:

english

File:

PDF, 4.19 MB

english, 1996

9

ChemInform Abstract: Use of Bicuculline, a GABA Antagonist, as a Template for the Development of a New Class of Ligands Showing Positive Allosteric Modulation of the GABAA Receptor.

Rodolphe Razet, Urs Thomet, Roman Furtmueller, Frantisek Jursky, Erwin Sigel, Werner Sieghart, Robert H. Dodd

Journal:

Year:

2001

File:

PDF, 32 KB

2001

10

GABAA receptor changes in δ subunit-deficient mice: Altered expression of α4 and γ2 subunits in the forebrain

Zechun Peng, Birgit Hauer, Robert M. Mihalek, Gregg E. Homanics, Werner Sieghart, Richard W. Olsen, Carolyn R. Houser

Journal:

The Journal of Comparative Neurology

Year:

2002

Language:

english

File:

PDF, 4.58 MB

english, 2002

11

Distribution of the major γ-aminobutyric acidA receptor subunits in the basal ganglia and associated limbic brain areas of the adult rat

Christoph Schwarzer, Ulrike Berresheim, Susanne Pirker, Anna Wieselthaler, Karoline Fuchs, Werner Sieghart, Günther Sperk

Journal:

The Journal of Comparative Neurology

Year:

2001

Language:

english

File:

PDF, 1.85 MB

english, 2001

12

Development of γ-aminobutyric acidergic synapses in cultured hippocampal neurons

Catherine Croft Swanwick, Namita R. Murthy, Zakaria Mtchedlishvili, Werner Sieghart, Jaideep Kapur

Journal:

The Journal of Comparative Neurology

Year:

2006

Language:

english

File:

PDF, 1.12 MB

english, 2006

13

GABA influences the development of the ventromedial nucleus of the hypothalamus

Tammy L. Dellovade, Aline M. Davis, Carolyn Ferguson, Werner Sieghart, Gregg E. Homanics, Stuart A. Tobet

Journal:

Developmental Neurobiology

Year:

2001

Language:

english

File:

PDF, 1.84 MB

english, 2001

14

Structure–activity relationship of etomidate derivatives at the GABAA receptor: Comparison with binding to 11β-hydroxylase

Erika Atucha, Friedrich Hammerschmidt, Ilse Zolle, Werner Sieghart, Michael L. Berger

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2009

Language:

english

File:

PDF, 257 KB

english, 2009

15

Use of bicuculline, a GABA antagonist, as a template for the development of a new class of ligands showing positive allosteric modulation of the GABAA receptor

Rodolphe Razet, Urs Thomet, Roman Furtmüller, Frantisek Jursky, Erwin Sigel, Werner Sieghart, Robert H Dodd

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2000

Language:

english

File:

PDF, 144 KB

english, 2000

16

Initially expressed early rat embryonic GABAA receptor Cl– ion channels exhibit heterogeneous channel properties

Ruggero Serafini, Wu Ma, Dragan Maric, Irina Maric, Fatiha Lahjouji, Werner Sieghart, Jeffery L. Barker

Journal:

European Journal of Neuroscience

Year:

1998

Language:

english

File:

PDF, 1.09 MB

english, 1998

17

Clusters of GABAA receptors on cultured hippocampal cells correlate only partially with functional synapses

Kai Kannenberg, Werner Sieghart, Harald Reuter

Journal:

European Journal of Neuroscience

Year:

1999

Language:

english

File:

PDF, 442 KB

english, 1999

18

Alterations in the expression of GABAA receptor subunits in cerebellar granule cells after the disruption of the α6 subunit gene

Zoltan Nusser, Zahida Ahmad, Verena Tretter, Karoline Fuchs, William Wisden, Werner Sieghart, Peter Somogyi

Journal:

European Journal of Neuroscience

Year:

1999

Language:

english

File:

PDF, 840 KB

english, 1999

19

Role of the GABAA receptor γ2 subunit in the development of gonadotropin-releasing hormone neurons in vivo

Sharon X. Simonian, Michael J. Skynner, Werner Sieghart, Christian Essrich, Bernhard Luscher, Allan E. Herbison

Journal:

European Journal of Neuroscience

Year:

2000

Language:

english

File:

PDF, 989 KB

english, 2000

20

Binding of γ-Aminobutyric AcidA Receptors to Tubulin

Chike Item, Werner Sieghart

Journal:

Journal of Neurochemistry

Year:

1994

Language:

english

File:

PDF, 814 KB

english, 1994

21

Bidirectional Alterations of GABAA Receptor Subunit Peptide Levels in Rat Cortex During Chronic Ethanol Consumption and Withdrawal

Leslie L. Devaud, Jean-Marc Fritschy, Werner Sieghart, A. Leslie Morrow

Journal:

Journal of Neurochemistry

Year:

1997

Language:

english

File:

PDF, 705 KB

english, 1997

22

Association of protein kinase C with GABAA receptors containing α1 and α4 subunits in the cerebral cortex: selective effects of chronic ethanol consumption

Sandeep Kumar, Werner Sieghart, A. Leslie Morrow

Journal:

Journal of Neurochemistry

Year:

2002

Language:

english

File:

PDF, 240 KB

english, 2002

23

Identification of an amino acid sequence within GABAA receptor β3 subunits that is important for receptor assembly

Noosha Ehya, Isabella Sarto, Leila Wabnegger, Thomas Klausberger, Werner Sieghart

Journal:

Journal of Neurochemistry

Year:

2003

Language:

english

File:

PDF, 246 KB

english, 2003

24

Subunit composition and quantitative importance of GABAA receptor subtypes in the cerebellum of mouse and rat

Angelika Pöltl, Birgit Hauer, Karoline Fuchs, Verena Tretter, Werner Sieghart

Journal:

Journal of Neurochemistry

Year:

2003

Language:

english

File:

PDF, 284 KB

english, 2003

25

Fear learning triggers structural changes at GABAergic synapses in the basal amygdala

Yu Kasugai, Markus Hauschild, Werner Sieghart, Ryuichi Shigemoto, Nicolas Singewald, Francesco Ferraguti

Journal:

BMC Pharmacology

Year:

2010

Language:

english

File:

PDF, 98 KB

english, 2010

26

Fear learning induces structural and functional plasticity at GABAergic synapses in the basolateral amygdala

Yu Kasugai, Elisabeth Vogel, Markus Hauschild, Ramon O Tasan, Yvan Peterschmitt, Andreas Lüthi, Ryuichi Shigemoto, Werner Sieghart, Nicolas Singewald, Günther Sperk, Francesco Ferraguti

Journal:

BMC Pharmacology

Year:

2011

Language:

english

File:

PDF, 83 KB

english, 2011

27

Benzodiazepines modulate GABAAreceptors by reducing a gamma-subunit-mediated inhibition of GABA sensitivity

Igor Baburin, Sophia Khom, Eugen Timin, Annette Hohaus, Werner Sieghart, Steffen Hering

Journal:

BMC Pharmacology

Year:

2009

Language:

english

File:

PDF, 113 KB

english, 2009

28

No proof of linkage between schizophrenia-related disorders including schizophrenia and chromosome 2q21 region

Harald N. Aschauer, Gabriele Fischer, Keith E. Isenberg, Kurt Meszaros, Ulrike Willinger, Richard D. Todd, Henriette Beran, Rainer Strobl, Manuela Lang, Karoline Fuchs, Werner Sieghart, Theodore Reich

Journal:

European Archives of Psychiatry and Clinical Neuroscience

Year:

1993

Language:

english

File:

PDF, 664 KB

english, 1993

29

In vivo and in vitro evaluation of [18F]FETO with respect to the adrenocortical and GABAergic system in rats

Markus Mitterhauser, Wolfgang Wadsak, Leila Wabnegger, Werner Sieghart, Helmut Viernstein, Kurt Kletter, Robert Dudczak

Journal:

European Journal of Nuclear Medicine and Molecular Imaging

Year:

2003

Language:

english

File:

PDF, 239 KB

english, 2003

30

Immunocytochemical Localization of the α1 and β2/3 Subunits of the GABAA Receptor in Relation to Specific GABAergic Synapses in the Dentate Gyrus

Zoltan Nusser, J. David B. Roberts, Agnes Baude, J. Grayson Richards, Werner Sieghart, Peter Somogyi

Journal:

European Journal of Neuroscience

Year:

1995

Language:

english

File:

PDF, 7.11 MB

english, 1995

31

Anatomical Gradients in Proliferation and Differentiation of Embryonic Rat CNS Accessed by Buoyant Density Fractionation: α3, β3 and γ2 GABAA Receptor Subunit Co-expression by Post-mitotic Neocortical Neurons Correlates Directly with Cell Buoyancy

Dragan Maric, Irina Maric, Wu Ma, Fatiha Lahojuji, Roland Somogyi, Xiling Wen, Werner Sieghart, Jean-Marc Fritschy, Jeffery L. Barker

Journal:

European Journal of Neuroscience

Year:

1997

Language:

english

File:

PDF, 2.44 MB

english, 1997

32

Behavioural correlates of an altered balance between synaptic and extrasynaptic GABAAergic inhibition in a mouse model

Saku T. Sinkkonen, Olga Y. Vekovischeva, Tommi Möykkynen, Waltraud Ogris, Werner Sieghart, William Wisden, Esa R. Korpi

Journal:

European Journal of Neuroscience

Year:

2004

Language:

english

File:

PDF, 407 KB

english, 2004

33

Quantitative localisation of synaptic and extrasynaptic GABAA receptor subunits on hippocampal pyramidal cells by freeze-fracture replica immunolabelling

Yu Kasugai, Jerome D. Swinny, J. David B. Roberts, Yannis Dalezios, Yugo Fukazawa, Werner Sieghart, Ryuichi Shigemoto, Peter Somogyi

Journal:

European Journal of Neuroscience

Year:

2010

Language:

english

File:

PDF, 1.20 MB

english, 2010

34

Localization of GABA-A receptor alpha subunits on neurochemically distinct cell types in the rat locus coeruleus

Nicole L. Corteen, Tomilola M. Cole, Ayshia Sarna, Werner Sieghart, Jerome D. Swinny

Journal:

European Journal of Neuroscience

Year:

2011

Language:

english

File:

PDF, 1.46 MB

english, 2011

35

Differential regulation of synaptic GABAA receptors by cAMP-dependent protein kinase in mouse cerebellar and olfactory bulb neurones

Zoltan Nusser, Werner Sieghart, Istvan Mody

Journal:

The Journal of Physiology

Year:

1999

Language:

english

File:

PDF, 1.13 MB

english, 1999

36

Neuronal Localization of Ca2+-dependent Protein Phosphorylation in Brain

Werner Sieghart, Howard Schulman, Paul Greengard

Journal:

Journal of Neurochemistry

Year:

1980

Language:

english

File:

PDF, 561 KB

english, 1980

37

Glutamate-Stimulated Phosphorylation of a Specific Protein in P2 Fractions of Rat Cerebral Cortex

Werner Sieghart

Journal:

Journal of Neurochemistry

Year:

1981

Language:

english

File:

PDF, 1.75 MB

english, 1981

38

Evidence for the Existence of Differential O-Glycosylated α5-Subunits of the γ-Aminobutyric AcidA Receptor in the Rat Brain

Werner Sieghart, Chike Item, Andrea Buchstaller, Karoline Fuchs, Harald Höger, Dieter Adamiker

Journal:

Journal of Neurochemistry

Year:

1993

Language:

english

File:

PDF, 634 KB

english, 1993

39

Antibodies Specific for GABAA Receptor α Subunits Reveal that Chronic Alcohol Treatment Down-Regulates α-Subunit Expression in Rat Brain Regions

Molina C. Mhatre, Gina Pena, Werner Sieghart, Maharaj K. Ticku

Journal:

Journal of Neurochemistry

Year:

1993

Language:

english

File:

PDF, 1.01 MB

english, 1993

40

Investigation of the abundance and subunit composition of GABAA receptor subtypes in the cerebellum of α1-subunit-deficient mice

Waltraud Ogris, Reinhard Lehner, Karoline Fuchs, Birgit Furtmüller, Harald Höger, Gregg E. Homanics, Werner Sieghart

Journal:

Journal of Neurochemistry

Year:

2006

Language:

english

File:

PDF, 179 KB

english, 2006

41

Identification of amino acid residues important for assembly of GABAA receptor α1 and γ2 subunits

Isabella Sarto-Jackson, Joachim Ramerstorfer, Margot Ernst, Werner Sieghart

Journal:

Journal of Neurochemistry

Year:

2006

Language:

english

File:

PDF, 474 KB

english, 2006

42

AMPA and kainate receptors mediate mutually exclusive effects on GABAA receptor expression in cultured mouse cerebellar granule neurones

Helen L. Payne, Jane H. Ives, Werner Sieghart, Christopher L. Thompson

Journal:

Journal of Neurochemistry

Year:

2008

Language:

english

File:

PDF, 814 KB

english, 2008

43

GABAA, Receptor α1, α4, and β3 Subunit mRNA and Protein Expression in the Frontal Cortex of Human Alcoholics

Hiroki Mitsuyama, Karley Y. Little, Werner Sieghart, Leslie L. Devaud, A. Leslie Morrow

Journal:

Alcoholism: Clinical and Experimental Research

Year:

1998

Language:

english

File:

PDF, 865 KB

english, 1998

44

Calcium-dependent protein phosphorylation during secretion by exocytosis in the mast cell

SIEGHART, WERNER, THEOHARIDES, THEOHARIS C., ALPER, SETH L., DOUGLAS, WILLIAM W., GREENGARD, PAUL

Journal:

Year:

1978

File:

PDF, 380 KB

1978

45

Molecular heterogeneity of benzodiazepine receptors

Sieghart, Werner, Karobath, Manfred

Journal:

Year:

1980

File:

PDF, 380 KB

1980

46

From synapse to behavior: rapid modulation of defined neuronal types with engineered GABAA receptors

Wulff, Peer, Goetz, Thomas, Leppä, Elli, Linden, Anni-Maija, Renzi, Massimiliano, Swinny, Jerome D, Vekovischeva, Olga Y, Sieghart, Werner, Somogyi, Peter, Korpi, Esa R

Journal:

Nature Neuroscience

Year:

2007

Language:

english

File:

PDF, 712 KB

english, 2007

47

Gel-based mass spectrometric analysis of a strongly hydrophobic GABAA-receptor subunit containing four transmembrane domains

Kang, Sung-Ung, Fuchs, Karoline, Sieghart, Werner, Pollak, Arnold, Csaszar, Edina, Lubec, Gert

Journal:

Nature Protocols

Year:

2009

Language:

english

File:

PDF, 492 KB

english, 2009

48

Dual mode of stimulation by the β-carboline ZK 91085 of recombinant GABAA receptor currents: molecular determinants affecting its action

Urs Thomet, Roland Baur, Petra Scholze, Werner Sieghart, Erwin Sigel

Journal:

British Journal of Pharmacology

Year:

1999

Language:

english

File:

PDF, 259 KB

english, 1999

49

A novel positive allosteric modulator of the GABAA receptor: the action of (+)-ROD188

Urs Thomet, Roland Baur, Rodolphe Razet, Robert H Dodd, Roman Furtmüller, Werner Sieghart, Erwin Sigel

Journal:

British Journal of Pharmacology

Year:

2000

Language:

english

File:

PDF, 184 KB

english, 2000

50

Diazepam-bound GABAA receptor models identify new benzodiazepine binding-site ligands

Richter, Lars, de Graaf, Chris, Sieghart, Werner, Varagic, Zdravko, Mörzinger, Martina, de Esch, Iwan J P, Ecker, Gerhard F, Ernst, Margot

Journal:

Nature Chemical Biology

Year:

2012

Language:

english

File:

PDF, 2.07 MB

english, 2012

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